Pharmacology Jobs in Chennai

Role Title: AT-GTEL, Chennai Line: Scientist (Chem Analytical) Global Job levels Job Family Group: Research and Development Job Family: 093- Chemistry-Analytical Job Category: Research Job Level: R01 - Associate Scientist Job Code: 600061 Management Level: J040 (04B) Why Patients Need You Pfizer s purpose is to deliver breakthroughs that change patients lives. Research and Development is at the heart of fulfilling Pfizer s purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best in class medicines to patients around the world. Accountability: Responsible for Analytical Method development, Method Validation (for E&L workflow support is preferred), Method transfer, Routine analytical and stability study support for API, Intermediates and different DP formulations with the guidance and mentorship by senior chemist or supervisor. What You Will Achieve As a Scientist, you will be at the center of our operations and you ll find that everything we do, every day, is in line with an unwavering commitment to quality. With your deep knowledge in the discipline, you will be an active team member who influences at the project team level. You will perform qualitative and quantitative analyses of organic, inorganic compounds, or biologics to determine chemical and physical properties during chemical syntheses, fermentation or drug product development process. You will be using your scientific judgment to adapt standard methods and techniques by applying prior work experience and consulting others. Your ability to plan will help in preparing short-term work activities on projects. Your creativity in developing novel processes and new ideas will be used frequently. You will undertake mentoring activities to guide your team members. It is your hard work and focus that will help in making Pfizer ready to achieve new milestones and help patients across the globe. Responsibilities: He should adhere both quality and safety compliance according to organizational policies/procedures and regulatory guidelines. Responsible for development analytical methods and analytical method validation by UPLC, HPLC, GC, for API, DP, Intermediate and Raw materials. Working on E&L workflow is preferred. Test According to International Standards: Extractables & Leachables assessments for finished packaging: EMA, US-FDA, USP , , recommendations of PQRI Migrations-/simulated use studies Leachables shelf-life studies (GMP/cGMP studies) Should be conversant with the below analytical Techniques Headspace coupled to gas chromatography with mass spectral detection (HS-GC/MS) Gas chromatography with a mass spectral detection (GC/MS) Liquid chromatography with a diode array detection combined with mass spectral detection (HPLC-UV/MS) Liquid chromatography with multiple order mass spectral detection (LC/MS/MS) Inductively coupled plasma with optical emission detection (ICP-OES) and ICP-MS. UV/VIS Spectrophotometry Wet chemical methods: pH, TOC, conductivity, and others Other experiences: Ensure technical output is compliant with all Global Training Curricula for the instrument operations, material handling and certifications related to, Quality Ops, Manufacturing and EHS. Ensures compliance to local and corporate procedures and ensures all data packages are audit ready and transferable. Coordinate with cross functional teams to ensure timely execution and resolution of all deliverables versus target milestones. Requirements for all Global Job Levels Preferred Qualifications MSc/M Pharm/ Ph.D Preferred years of experience 2 to 4 years of Experience Experience with interdisciplinary drug development teams and industrial experience developing analytical strategies and methods in support of product and process development and to assess the quality and characteristics of biotherapeutics Experience working in a regulated environment, such as Good Laboratory Practices {part of GxP} Effective verbal and written communication skills Relationships: Small Molecule Technology Global Technology & Engineering Global Supply Chain Regulatory Sciences Global EHS Pharmaceutical Sciences Small Molecule Contract Research, Development and Manufacturing Organizations Academic Institutes Pfizer is an equal opportunity employer and complies with all applicable equal employment opportunity legislation in each jurisdiction in which it operates. Research and Development #LI-PFE Qualification : MSc/M Pharm/ Ph.D

State of the art knowledge of modern synthetic methodology, including aspects of asymmetric synthesis, green chemistry, catalysis, and physical organic chemistry as it relates to reaction mechanism is expected. Contemporary knowledge of drug development, the pharmaceutical industry, and fundamental principles of process development from a laboratory and manufacturing perspective. Strong track record of successful delivery of projects, using sound scientific analysis and judgment to advance programs Good interpersonal skills Experience of leading small teams of 5-8 chemists, mentoring and directing other colleagues. Excellent oral and written communication skills, including the ability to maintain an accurate scientific notebook, and draft concise emails, written reports, publications, synthesis information packages and related documents Rational, innovative and creative approach to problem solving. Job location: Onsite, Chennai Lead a group of 5-8 process chemists at an external partner located in India to deliver phase-appropriates processes and vendor synthetic information packages (VSIPs) for Pfizer s Drug-Linker portfolio. Use extensive technical knowledge and experience in state-of-the-art organic and process chemistry to develop safe, sustainable, robust, cost-efficient, and phase-appropriate process that are aligned with internal business needs. Develop strategic plan to develop and implement purification and separation capabilities at the external partner that is driven by drug linkers portfolio needs with internal stakeholders. Work collaboratively and effectively, building and leading high performing teams Ensure accurate and timely documentation of experimental work, and clear and concise presentation of work to stakeholders both internally and externally. Co-ordinate work with other functions (Process safety, engineering, analytical)/ departments to achieve project objectives. Build a strong interface and network with Pfizer s Chemical Process and Analytical Development group (Global Chemical Research and Development) and keep up to date with synthetic and technology advancements. Support in designing and refining workflows and metrics. Look for opportunities to align, share and implement best practices. Contribute to the development of a strong scientific, process chemistry, safety and quality culture within the chemistry labs. Master s degree in Chemistry, Chemical Engineering or a related field and 10+ years of experience in process chemistry research and development towards New Chemical Entities (APIs) or fine chemicals or PhD in Organic Chemistry or a related field with 6+ years of experience in process chemistry research and development towards New Chemical Entities (APIs) or fine chemicals Develop state of the art purification strategies and capabilities for complex synthetic molecules such as Drug-Linkers. Plan the scientific direction of projects by providing high quality experimental planning, evaluation and characterization of chromatography purification and synthetic processes. Work Location: Onsite, Pfizer Chennai Pfizer is an equal opportunity employer and complies with all applicable equal employment opportunity legislation in each jurisdiction in which it operates. Research and Development Qualification : Masters degree in Chemistry, Chemical Engineering or a related field and 10+ years of experience in process chemistry research and development towards New Chemical Entities (APIs) or fine chemicalsorPhD in Organic Chemistry or a related field with 6+ years of experience in process chemistry research and development towards New Chemical Entities (APIs) or fine chemicals