Associate Scientist Job in Syngene International

JOB DESCRIPTION

Designation: Associate Scientist-Protein Biology

Job Location: Bangalore

Department: Discovery Biology

About Syngene

Incorporated in 1993, Syngene International Ltd. is an innovation-focused global discovery, development and manufacturing organization providing integrated scientific services to the pharmaceutical, biotechnology, nutrition, animal health, consumer goods and specialty chemical industries around the world. Syngene s clientele includes world leaders such as Bristol-Myers Squibb, Baxter, Amgen, GSK, Merck KGaA and Herbalife. Its innovative culture is driven by the passion of its 4240- strong team of scientists who work with clients from around the world to solve their scientific problems, improve R&D productivity, speed up time to market and lower the cost of innovation.

Job Purpose:

The incumbent will perform protein purification and characterization from various expression systems.

Key Responsibilities:

• Independently perform protein purification from various expression systems (Mammalian, E. coli & Insect cell) and QC.
• Prepare detailed reports for sharing with clients and attend telecons.
• Improve lab efficiency and streamlines the operational processes to increase productivity.
• Analyze operational problems, identify solutions, and implement corrective actions.
• Guide and train research scientists in the team at various levels.
• Follow environment, health, and safety (EHS) requirements at all times in the workplace ensuring individual and lab/plant safety
• Attend training on environment, health, and safety (EHS) measures imparted company

Educational Qualification:

M.Sc/ M.Tech/MS (Biotechnology, Biochemistry or a related discipline)

Technical and Functional skills:

• Expertise in routine protein purification with affinity, size exclusion, ion exchange chromatography using AKTA FPLC systems (Unicorn software).
• Expertise in protein purification of antibodies, affinity-tagged, secreted proteins as well as "problematic" proteins (low expression, poor solubility, intra-cellular expression, prone to aggregation).
• Proficiency in protein extraction and solubilization methods, protein refolding and purification via affinity, hydrophobic interaction (HIC), ion exchange (IEX), size exclusion (SEC) and mixed-mode chromatography.
• Expertise in routine characterization of proteins includingSDS-PAGE, SE-HPLC, and biophysical techniques.
• Familiarity with mammalian and microbial protein expression is a plus

Experience:

• 5-7 years of relevant experience in Biotech/Pharma/R&D

Behavioral Skills:

Be polite, assertive and collaborate well with colleagues

Take accountability and ownership for respective job function

Good verbal and written communication skills

Equal Opportunity Employer:

It is the policy of Syngene to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by applicable legislation or local law. In addition, Syngene will provide reasonable accommodations for qualified individuals with disabilities.